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目的研究缺血修饰清蛋白(IMA)、超敏肌钙蛋白T(HS-CTNT)、肌酸激酶同工酶(CK-MB)血清水平在急性冠状动脉综合征(ACS)危险分层中的意义。方法测定190例对照组与601例ACS患者(其中包括低危组、中危组、高危组)IMA、HS-CTNT、CK-MB的血清水平。结果低危组、中危组、高危组间IMA水平随危险程度的升高而升高,低危组与高危组之间比较差异有统计学意义(P<0.05),中危组与高危组、低危组之间比较差异无统计学意义(P>0.05),低危组、中危组、高危组与对照组之间比较差异有统计学意义(P<0.05);低危组、中危组、高危组及对照组彼此之间HS-CTNT、CK-MB血清水平比较差异有统计学意义(P<0.05),且随着危险程度的增加,HS-CTNT、CK-MB血清水平不断增高。结论 HS-CTNT、CK-MB、IMA在ACS危险分层及诊断中有一定的临床意义。
Objective To investigate the serum levels of IMA, hs-CTNT and CK-MB in the risk stratification of acute coronary syndrome (ACS) significance. Methods The serum levels of IMA, HS-CTNT and CK-MB in 190 control subjects and 601 ACS patients (including low-risk group, intermediate-risk group and high-risk group) were determined. Results The levels of IMA in low-risk group, intermediate-risk group and high-risk group increased with the increase of the degree of risk, while the difference between low-risk group and high-risk group was statistically significant (P <0.05) (P> 0.05). There was significant difference between low-risk group, moderate-risk group and high-risk group and control group (P <0.05) Serum levels of HS-CTNT and CK-MB were significantly different between the high-risk group and the high-risk group and the control group (P <0.05). Serum levels of HS-CTNT and CK-MB were continuously increased with the increase of the risk level Increase. Conclusion HS-CTNT, CK-MB and IMA have some clinical significance in the risk stratification and diagnosis of ACS.