一、细菌感染疾病细菌性感染性疾病化学疗法的主要药物依然是β-内酰胺制剂,其作用机制及耐药机构也已有详尽报道。随着β-内酰胺尤其是第二、第三代头孢菌素的广泛应用,出现了具有新的耐药机构的金葡菌,因而对这种抗甲氧青霉素(MRSA)的金葡菌(MRSA)的对策是当今的新课题。此外还有吡啶酮羧酸系合成抗生素的进展。当前,不管是β-内酰胺,还是新合成的抗生素,仅从抗菌力来说,大体上达到了完满的程度,对感染防御能力无缺陷的宿主的感染性疾病,己经进入了可以完全治愈的时代。但是治疗感染症与宿主有很 First, the bacterial infection diseases Bacterial infectious diseases The main drug chemotherapy is still β-lactam preparations, its mechanism of action and drug resistance agencies have also been fully reported. With the widespread use of β-lactams, especially the second and third generation cephalosporins, S. aureus with a new drug-resistant mechanism has emerged, so this S. aureus (MRSA) MRSA) response is a new topic today. In addition there are pyridine ketone carboxylic acid synthesis of antibiotics progress. At present, both β-lactams and newly synthesized antibiotics have reached an almost complete extent only from the antibacterial power, and infectious diseases of hosts that are non-defective in the defense against infection have entered a state of complete cure Era. But the treatment of infectious diseases and the host is very