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目的为选择治疗宫颈糜烂的高效、简便、低毒或无毒副作用的药物和最佳剂型。方法176例宫颈糜烂患者随机分为药膜组和栓剂组,分别以复方氟哌酸药膜和栓剂进行治疗。以临床检查、细胞学检查及用药反应等项指标进行对照观察。统计学处理采用卡方检验。结果药膜组对宫颈糜烂总有效率为90.83%,栓剂组为76.79%、药膜组疗效优于栓剂组(P<0.05)。结论复方氟哌酸的两种剂型均可用于治疗宫颈糜烂,用药量小,无全身毒副作用,造价低,操作简便。药膜是治疗宫颈糜烂较为理想的剂型。
The purpose is to choose the treatment of cervical erosion efficient, simple, low toxicity or non-toxic side effects of drugs and the best dosage form. Methods One hundred and seventy-six patients with cervical erosion were randomly divided into two groups: drug film group and suppository group, which were treated with compound norfloxacin film and suppository respectively. To clinical examination, cytology and medication response and other indicators for control observation. Statistical analysis using chi-square test. Results The total effective rate of the film group on cervical erosion was 90.83% and that of the suppository group was 76.79%. The efficacy of the film group was better than that of the suppository group (P <0.05). Conclusion Both of the two formulations of norfloxacin can be used for the treatment of cervical erosion, with small dosage, no systemic side effects, low cost and easy operation. Membrane is the treatment of cervical erosion is the ideal form.