创伤是脑脊液鼻漏最常见的原因。非创伤性的少见,可分为两类:一类有颅内高压,常为颅内肿瘤特别是垂体瘤;另一类颅内压正常,多为筛板或蝶鞍区有先天性异常和萎缩病灶(可能因局部缺血)而致。医原性者则构成另外重要的一类。本文报告一例脑脊液鼻漏患者相信与长期使用可卡因吸人有关,而这种原因引起的鼻漏过去未有过报告。患者男性34岁,因鼻分泌物和全身不适6天而就医,诉鼻分泌物清亮带咸味,夜间常沾污枕头,双鼻嗅觉缺失,这些症状在鼻内吸人可卡因后明显,并述过去19年来每年吸入可卡因7次,但无头外伤史。检查证实液体来自筛板区,无其他病理性神经系体征,血常规和培养阴性,头颅 Trauma is the most common cause of cerebrospinal rhinorrhea. Non-invasive rare, can be divided into two categories: one type of intracranial hypertension, often intracranial tumors, especially pituitary tumors; the other type of normal intracranial pressure, mostly in the sieve or sellar area with congenital anomalies and Shrinking lesions (probably due to ischemia) caused. Medical principles constitute another important category. This article reports a case of cerebrospinal rhinorrhea in patients believed to be associated with long-term use of cocaine inhalation, and this cause of rhinorrhea has not been reported in the past. The 34-year-old man sought medical treatment for nasal secretions and general malaise for six days. He complained of nasal secretions with salty clarity, frequent night-time contamination of the pillow, and lack of double-nasal smell. These symptoms were evident after intranasal inhalation of cocaine, Cocaine has been ingested seven times a year for the past 19 years but without a history of head injury. Check confirmed fluid from the plate area, no other signs of pathological neurological disorders, blood and culture negative, head