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目的：探讨除血Ｃｒ、Ｃｃｒ之外反映肾小球功能的临床简便易行的检验方法。方法：用ＲＩＡ方法检测了一组原发性肾小球疾病患者急性期、恢复期的α１－Ｍ值。结果：急性期α１－Ｍ值明显高于恢复期，有统计学意义，随病情好转，血α１－Ｍ亦下降。结论：血清α１－Ｍ可以作为观察原发性肾小球疾病病情变化的指标，α１－Ｍ升高，示病情加重，小球功能损害明显，反之，示病情好转，小球功能得到恢复
Objective: To investigate the clinical simple and convenient method to detect glomerular function except Cr and Ccr. Methods: The α1-M values of acute and convalescent patients in a group of primary glomerular diseases were detected by RIA method. Results: The value of α1-M in acute phase was significantly higher than that in convalescent phase, with statistical significance. As the condition improved, the blood α1-M also decreased. Conclusion: Serum α1-M can be used as an index to observe the changes of primary glomerular disease. The increase of α1-M shows the aggravating of disease and the impairment of glomerulus. On the contrary, it shows that the condition is improved and the pellet function is restored