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消化性溃疡(PU)的药物治疗原则:一是抑制攻击因子,即减少胃酸分泌及降低胃蛋白酶活性;二是增强防御因素,即提高组织抵抗力和促进组织修复功能。近年来治疗PU的新药不仅较多,而且传统药物及老药新用也有新的进展。本文综述近年文献,就临床研究较多,以及有一定疗效的新、老抗溃疡药物,选择介绍如下: 一、抑制攻击因子的药物1.呋喃硝胺(Ranitidine):为八十年代初国外合成的一种H_2受体拮抗剂。国内已能生产,并用于临
Peptic ulcer (PU) drug treatment principles: First, inhibit the attack factor, that is, reduce gastric acid secretion and reduce pepsin activity; the second is to enhance the defensive factors, that is, to improve tissue resistance and promote tissue repair function. In recent years, not only more new drugs for the treatment of PU, but also new uses of traditional drugs and old drugs have also made new progress. This review summarizes the recent literature, the more clinical research, as well as a certain effect of new and old anti-ulcer drugs, choose to introduce the following: First, inhibit the attack of the drug 1. Ranitidine (Ranitidine): for the early 1980s, foreign synthesis A H 2 receptor antagonist. Domestic has been able to produce, and for the Pro