恶性胸腔积液是癌症患者常见的并发症,多数属于疾病进展或复发的结果,也可作为癌症患者的首发临床表现[1]。常使患者出现不同程度的呼吸困难,严重影响患者的生活质量并危及生命。对化学治疗效果好的肿瘤,通过全身治疗有可能控制胸腔积液[1],但多数病例不能达到满意的疗效。故长 Malignant pleural effusion is a common complication of cancer patients, most of which are the result of disease progression or recurrence, but also as a first-line clinical manifestations of cancer patients [1]. Patients often appear to varying degrees of breathing difficulties, seriously affecting the quality of life of patients and life-threatening. For chemotherapy-effective tumors, it is possible to control pleural effusion through systemic treatment [1], but most cases can not achieve satisfactory results. So long