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目的探讨经尿道膀胱电切术(transurethral resection of bladder,TURBt)同期进行尿道前列腺切除术(transurethral resection of prostate,TURP)治疗的浅表性膀胱癌合并良性前列腺增生(benign prostate hyperplasia,BPH)的临床效果。方法回顾性分析本院手术治疗的109例浅表性膀胱癌合并BPH患者的资料情况,其中采取TURBt同期行TURP治疗的患者57例(联合组)、仅采取TURBt资料52例(对照组),对比两组患者的手术效果就围手术期指标。结果联合组的手术时间、术中出血量、术后留置导尿管时间、术后住院时间均显著的长于对照组患者,且差异具有统计学意义(P<0.05);术后联合组的国际前列腺症状(international prostate symptom score,IPSS)评分、生存质量(quality of life score,QOL)评分、残余尿量(residual urine volume,PVR)测定值均显著的低于对照组患者(P<0.05),联合组的Qmax测定值显著地高于对照组患者(P<0.05);术后24个月,联合组和对照组的肿瘤复发率差异无统计学意义(P>0.05),联合组的尿道狭窄发生率(3.51%)显著低于对照组患者(17.31%),且差异具有统计学意义(P<0.05)。结论 TURBt同期TURP治疗的浅表性膀胱癌合并BPH虽然手术时间、出血量较多及术后恢复时间长较单纯TURBt,但是具有显著的改善患者术后排尿情况、生存质量及降低尿道狭窄发生率的作用。
Objective To investigate the clinical efficacy of transurethral resection of bladder (TURBt) in the treatment of superficial bladder cancer complicated with benign prostatic hyperplasia (BPH) treated with transurethral resection of prostate (TURP) effect. Methods The data of 109 patients with superficial bladder cancer complicated with BPH undergoing surgical treatment in our hospital were analyzed retrospectively. TURBt 57 patients (combination group) and TURBt 52 patients (control group) Comparison of the two groups of patients on the perioperative outcome of surgical indicators. Results The operation time, intraoperative blood loss, postoperative indwelling catheter and postoperative hospital stay were significantly longer in the combined group than in the control group (P <0.05). The postoperative combined international The scores of IPRS score, QOL score and residual urine volume (PVR) were significantly lower than those of the control group (P <0.05) The Qmax of the combined group was significantly higher than that of the control group (P <0.05). There was no significant difference in the recurrence rate between the combined group and the control group (P> 0.05) 24 months after the operation. The urethral stricture (3.51%) was significantly lower than the control group (17.31%), and the difference was statistically significant (P <0.05). Conclusions TURBt TURP treatment of superficial bladder cancer combined with BPH has a significant improvement in postoperative urination, quality of life and the incidence of urethral stricture, although the operation time, bleeding volume and postoperative recovery time are longer than those of TURBt alone Role.