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黄毛木皂甙５０～１５０ｍｇ·ｋｇ￣－１灌胃给药５～７ｄ对正常小鼠、肾上腺素性高血糖小鼠及四氧嘧啶性糖尿病小鼠可产生明显的降血糖作用。对葡萄糖性高血糖小鼠，其降血糖作用不明显。对四氧嘧啶性糖尿病大鼠的葡萄糖耐量无明显影响。
50 ~ 150mg · kg ~ -1 Salvia saponin administered intragastrically for 5 ~ 7d on normal mice, adrenergic hyperglycemia mice and alloxan-induced diabetic mice can produce significant hypoglycemic effect. Glucose-induced hyperglycemia in mice, its hypoglycemic effect is not obvious. No significant effect on glucose tolerance in alloxan-induced diabetic rats.