松驰素(relaxin)在妇产科是已知的名称。1926年Hisaw等首先发现并证明,有些动物在分娩过程中,耻骨联合的松解分离系受一种活性物质调节。1930年Fevold和Hisaw等发现猪黄体提取物能使去卵巢、经雌激素准备的豚鼠耻骨韧带发生分离,而称之为松弛素。虽从松弛素概念的提出至今已经过半个多世纪,但研究进展不大,原因是多方面的。有人曾制成了猪的松弛素粗制品,试图 Relaxin is a known name in obstetrics and gynecology. In 1926, Hisaw et al. First discovered and proved that in some animals during labor, the pubic symphysis release system is regulated by an active substance. In 1930, Fevold and Hisaw found swine luteum extract can make ovariectomized estrogen-prepared guinea pig pubic ligaments separation, which is called relaxin. Although it has been more than half a century since the concept of relaxin was proposed, there has been little research progress for many reasons. Someone had made a crude product of pigs relaxin, trying to