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目的：通过4种化疗方法的分析比较，了解动脉化疗在妇科恶性肿瘤化疗中的价值。材料与方法：40例妇科恶性肿瘤分成两组（卵巢肿瘤组和子宫肿瘤组），按4种不同途径行反复多次化疗，包括42次单一静脉化疗，124次静脉加腹腔化疗，106次单一动脉化疗，48次动脉化疗后再行静脉加腹腔联合化疗。结果：对卵巢恶性肿瘤采用多途径联合用药化疗近期疗效最佳（P＜0.01），单一动脉化疗与静脉加腹腔联合化疗比较无差异（P＞0.05）；对子宫恶性肿瘤采用单一动脉化疗及多途径联合化疗均较其他化疗方式近期疗效显著（P＜0.01），单一静脉化疗在二类肿瘤中疗效最差（P＜0.01）。结论：动脉化疗结合静脉和腹腔联合化疗可以提高妇科恶性肿瘤的近期疗效，对卵巢恶性肿瘤尤其重要，但单一动脉化疗对卵巢恶性肿瘤无特异性，而对子宫恶性肿瘤有价值。
Objective: To understand the value of arterial chemotherapy in the chemotherapy of gynecologic malignancies through the analysis and comparison of four chemotherapy methods. Materials and Methods: Forty patients with gynecologic malignancies were divided into two groups (ovarian tumor group and uterine tumor group), and repeated chemotherapy was performed according to 4 different routes including 42 single intravenous chemotherapy, 124 intravenous plus intraperitoneal chemotherapy, and 106 single-use chemotherapy. Arterial chemotherapy, 48 arterial chemotherapy followed by intravenous plus intraperitoneal chemotherapy. RESULTS: The short-term curative effect of multi-modality combined chemotherapy for ovarian malignant tumors was the best (P<0.01). There was no difference between single-arterial chemotherapy and intravenous plus intraperitoneal chemotherapy (P>0.05). Single-arterial chemotherapy was used for uterine malignant tumors. Combination chemotherapy was more effective than other chemotherapy in the short term (P<0.01), and single intravenous chemotherapy was the worst in the two types of cancer (P<0.01). Conclusion: Arterial chemotherapy combined with intravenous and intraperitoneal chemotherapy can improve the short-term efficacy of gynecological malignancy. It is particularly important for malignant ovarian tumors, but single-arterial chemotherapy is not specific for ovarian malignancies, but is valuable for uterine malignancies.