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实验研究为了进一步探讨排石汤类药物对狗的胆汁分泌、胆道运动、肠道运动的作用机理,我们采用中西药物对照法进行狗的动物实验,今小结如下: (一)中药方剂的组成及药物制备: 方剂组成:茵陈、金钱草、鲜虎仗、木香、桅子、积壳、大黄、芒硝。药物制备:实验用300％煎剂。 (二)西药:10％去氧胆酸钠。实验材料和方法实验应用体重10公斤以上的健康犬。 (一)手术方法: 1.术前用3％戊巴比妥钠1ml/公斤静脉麻醉,右上腹肋缘切口,结扎胆囊管,将胆汁抽空,(检查胆汁成分),在胆囊颈部或底部作荷包缝合,切开后插入水囊,结扎固定,外接气泡浮标水压计,描记胆囊运动。 2.暴露胆总管,切开向上插入内径约2—3毫米塑料管深约1.5～2.0厘米,向下用同样内径
Experimental studies To further explore the mechanism of Paishitang drugs on bile secretion, biliary tract movement, and intestinal motility in dogs, we used the Chinese-Western drug control method to conduct animal experiments in dogs. The summary is as follows: (1) The composition of traditional Chinese medicine prescriptions and Drug Preparation: Formulation: capillaris, Lysimachia, fresh tiger scorpion, woody, gardenia, shell, rhubarb, Glauber’s salt. Drug preparation: 300% decoction used in the experiment. (b) Western medicine: 10% sodium deoxycholate. Experimental Materials and Methods Experiments were conducted on healthy dogs weighing more than 10 kg. (I) Surgical methods: 1. Intravenous anesthesia with 3% pentobarbital sodium 1ml/kg preoperatively, right upper abdominal margin incision, ligated cystic duct, evacuated bile, (check bile composition), at the neck or bottom of the gallbladder For purse-string suturing, the incision was opened and the balloon was inserted. The ligation was fixed and an external bubble buoy hydrostatic pressure gauge was used to trace the movement of the gallbladder. 2. Expose the common bile duct, incise and insert approximately 2-3 mm deep inside the plastic tube with a depth of about 1.5-2.0 cm, down the same inner diameter