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目的评价肾康注射液联合用药治疗肾小球肾炎合并急性间质性肾炎的临床效果。方法将2014年3月至2015年3月98例肾小球肾炎合并急性间质性肾炎患者纳入研究,按随机数字表法分为两组。对照组49例给予常规方法治疗,观察组49例给予肾康注射液联合用药治疗,对比两组临床治疗效果。结果观察组治疗总有效率(95.92%)明显高于对照组(75.51%),差异有统计学意义(P<0.05)。治疗前,两组24 h尿蛋白定量、尿素氮、血肌酐三项指标水平比较差异未见统计学意义(P>0.05);治疗后,两组上述三项指标水平均有所改善,但改善效果方面观察组明显更优(P<0.05)。观察组与对照组并发症发生率分别为4.08%、28.57%,两组比较差异有统计学意义(P<0.05)。结论对于肾小球肾炎合并急性间质性肾炎患者,给予肾康注射液联合用药治疗效果显著,值得在临床应用。
Objective To evaluate the clinical effect of Shenkang injection combined with drug treatment of glomerulonephritis with acute interstitial nephritis. Methods From March 2014 to March 2015, 98 cases of glomerulonephritis with acute interstitial nephritis were enrolled in the study and divided into two groups according to the random number table. The control group, 49 cases given conventional treatment, the observation group, 49 cases given Shen Kang injection combined with medication, compared the two groups of clinical treatment. Results The total effective rate (95.92%) in observation group was significantly higher than that in control group (75.51%), the difference was statistically significant (P <0.05). Before treatment, two groups of 24 h urinary protein, urea nitrogen, serum creatinine three indicators of the difference was not statistically significant (P> 0.05); after treatment, the two groups of the above three indicators have improved, but improved Effect observation group was significantly better (P <0.05). The complication rates of observation group and control group were 4.08% and 28.57% respectively, with significant difference between the two groups (P <0.05). Conclusion Glomerulonephritis patients with acute interstitial nephritis, given Shen Kang injection combined with significant therapeutic effect, it is worth in clinical application.