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依凡罗(Invenal)是新的糖尿病治疗剂,学名N~1—对氨基苯磺(?)基-N~2-正丁基脲,結構式:分子量:271.35。本品为無味無嗅微黄色结晶体,在乙醚氯彷中难溶,極易溶解在乙醇、丙酮中,稀酸和稀碱内亦可溶解。动物試驗结果,本品可以使血糖值迅速下降而且可以維持很久,空腹给与健康人最小有效量1～2克后,血糖值即有輕度的下降,若給与糖尿病患者,則能使血糖值恢复正常。经口服后在人体内吸收非常迅速,其吸收率为100%。排洩很迟緩,主要由腎臟排洩,在24小时以内排洩較慢。当服后3～4小时以内,血液中药的濃度最高,所以第一次服3克以
Invenal is a new therapeutic agent for diabetes mellitus. Its scientific name is N ~ 1-p-aminobenzenesulfonyl-N ~ 2-n-butyl urea. Structural formula: molecular weight: 271.35. This product is tasteless odorless yellow crystals, insoluble in ether chloroform, easily dissolved in ethanol, acetone, dilute acid and dilute alkali can also be dissolved. Animal test results, the product can make the blood sugar value decreased rapidly and can be maintained for a long time, fasting to healthy people the minimum effective dose of 1-2 grams, the blood glucose value that there is a slight decline, if given to patients with diabetes, blood glucose can make Back to normal. After oral absorption in the human body very quickly, the absorption rate of 100%. Excretion is slow, mainly excreted by the kidneys, excretion slower within 24 hours. When served 3 to 4 hours later, the highest concentration of blood Chinese medicine, so the first service 3 grams