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目的分析宜昌市2010—2015年耐多药肺结核患者发现治疗情况,为下一步制定耐药肺结核防治策略提供依据。方法收集2010—2015年耐多药肺结核患者的相关资料,进行统计分析。结果 2010—2015年宜昌市共发现MDR-TB 218例,其中男性160例,占73.4%;女性58例,占26.6%;男女性别比为2.8∶1。职业以农民为主,占55.0%(120/218)。发现的耐多药肺结核患者中,纳入治疗153例(70.2%),各年间纳入治疗率有统计学差异(P<0.05)。6月末痰涂片阴转率为70.6%,6月末痰培养阴转率为50.3%,各年间6月末痰涂片阴转率有统计学差异(P<0.05),但6月末培养阴转率无统计学差异。完成疗程76例,治愈36例,治愈率47.4%。结论宜昌市通过实施国际项目在耐药结核病患者发现、诊疗和督导管理方面取得了很大成绩,但在病人纳入治疗和治疗效果方面仍需进一步完善。
Objective To analyze the treatment of MDR-TB patients in Yichang City from 2010 to 2015 and provide evidence for the future development of drug-resistant tuberculosis prevention and treatment strategies. Methods The data of MDR-TB patients from 2010 to 2015 were collected for statistical analysis. Results A total of 218 MDR-TB cases were found in Yichang City during 2010-2015, including 160 males (73.4%), 58 females (26.6%) and a male / female ratio of 2.8: 1. Occupation was dominated by peasants, accounting for 55.0% (120/218). Among the MDR-TB patients found, 153 cases (70.2%) were included in the treatment, and the treatment rates included in each year were statistically different (P <0.05). At the end of June, the negative conversion rate of sputum smear was 70.6%, and the negative conversion rate of sputum culture was 50.3% at the end of June. The negative conversion rate of sputum smear at the end of June was statistically different (P <0.05) No statistical difference. 76 cases completed the treatment, 36 cases were cured, the cure rate was 47.4%. Conclusion Yichang City has achieved great success in the management of drug discovery, diagnosis, treatment and supervision through the implementation of international projects. However, it still needs to be further improved in the aspects of treatment and treatment.