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目的观察局部雾化吸入布地奈德、利巴韦林与全身应用地塞米松和利巴韦林治疗小儿急性喉炎的效果及不良反应,探讨联合吸入布地奈德混悬液及利巴韦林治疗小儿急性喉炎的疗效。方法选择本院2009年1月～2010年11月住院确诊急性喉炎患儿68例,随机分为治疗组(35例)和对照组(33例)。在综合治疗基础上,治疗组给予布地奈德联合利巴韦林氧驱雾化吸入,对照组加予全身应用地塞米松和利巴韦林。观察比较两组患儿治疗效果。结果治疗组的疗效(犬吠样咳嗽、声嘶、喉鸣音、呼吸困难等症状缓解)与对照组比较,均明显优于对照组,有显著性差异(P<0.01)。结论布地奈德混悬液联合利巴韦林氧驱雾化吸入治疗小儿急性喉炎,效果明显,能有效缓解症状,缩短疗程,不良反应小。
Objective To observe the effect and adverse reactions of local inhalation of budesonide, ribavirin and systemic dexamethasone and ribavirin in the treatment of acute laryngitis in children and explore the effect of combined inhalation of budesonide suspension and ribavirin Therapeutic effect of acute laryngitis in children. Methods 68 cases of acute laryngitis diagnosed in our hospital from January 2009 to November 2010 were randomly divided into treatment group (35 cases) and control group (33 cases). On the basis of comprehensive treatment, the treatment group was given inhalation of budesonide combined with ribavirin oxygen inhalation, and the control group was given systemic dexamethasone and ribavirin. Observation and treatment of children with two groups were compared. Results The curative effect (bark-like cough, hoarseness, laryngeal sounds, dyspnea and other symptoms relieved) in the treatment group was significantly better than that in the control group (P <0.01). Conclusion Budesonide suspension combined with ribavirin oxygen inhalation inhalation treatment of children with acute laryngitis, the effect is obvious, can effectively relieve symptoms and shorten the course of treatment, adverse reactions.