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目的：探讨术前置入主动脉内球囊反搏（IABP）对高危冠心病患者冠状动脉旁路移植手术（CABG）预后的影响。方法选择2012年12月-2014年12月接受 CABG 的高危冠心病患者65例，根据患者 IABP 时间不同分为术前组20例、术中组25例、术后组20例。比较3组术后病死率、住院时间、ICU 停留时间、呼吸机使用时间、IABP 辅助时间、射血分数（EF）改善率（术后 EF/术前 EF）、室颤及胸腔积液发生率等指标。结果术前组病死率、腹腔积液发生率、室颤发生率分别为5.0%、0、0，均低于术中组的24.0%、20.0%、8.0%和术后组的45.0%、30.0%、25.0%，比较差异均有统计学意义（P ﹤0.05）。而术前组住院时间、ICU 停留时间、呼吸机使用时间、IABP 辅助时间、正性肌力药物使用时间均适于术中组与术后组，LVEF 改善率高于后2组，比较差异均有统计学意义（P ﹤0.05）。结论术前 IABP 可降低患者病死率、心肌梗死发生率，改善患者心功能，并缩短住院时间，术前应用 IABP 可使患者获益更大。“,”Objective To investigate the prognosis effect of preoperative placement of intra aortic balloon counterpul-sation(IABP)in high-risk patients with coronary bypass operation(CABG). Methods From December 2012 to December 2014,65 cases of high risk coronary heart disease patients underwent CABG were selected. According to the different time,they were divided into preoperative group(20 cases),intraoperative group(25 cases)and postoperative group(20 cases). The postoperative mortality,hospitalization time,ICU stay time,duration of mechanical ventilation,IABP auxiliary time,improve-ment rate of ejection fraction( EF)( postoperative EF/ preoperative EF),ventricular fibrillation and pleural effusion of 3 groups were compared. Results The preoperative mortality rate,incidence of peritoneal effusion and ventricular fibrillation were 5% ,0,0 respectively,which was lower than 24% ,20% ,8% of the intraoperative group and 45% 30% ,25% of postop-erative group,the differences were statistically significant(P ﹤ 0. 05). The hospitalization time,ICU stay time,duration of me-chanical ventilation,IABP auxiliary time,positive inotropic drugs use time of preoperative group were all suitable for intraoper-ative group and postoperative group,and the LVEF improvement rate was higher than that of the other 2 group,the differences were statistically significant(P ﹤ 0. 05). Conclusion The preoperative IABP can reduce the mortality and incidence of myo-cardial infarction,improve heart function of patients and shorten the time of hospitalization. The application of IABP can make patients get more benefit from it.