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结核杆菌感染中传染因子和宿主的相互作用相当复杂。约90%受感染者带有结核杆菌但不发病,促使其余10%感染者近期或远期发病的因素尚不清楚,在结核病复发时某些病人的结核菌素皮肤试验表现为暂时的无反应性。本文是根据作者实验室对人类结核免疫无反应性研究的结果作一综述。一、正确认识结核病结核病是最早被发现的疾病之一,随着有效化疗药的发现,结核病的研究进入了低潮。事实上,世界人口的一半是结核菌素反应者,表明已感染过结核菌。据估计每年出现
Infection with M. tuberculosis infection and host interaction is quite complex. About 90% of those infected with Mycobacterium tuberculosis but not disease, contributing to the remaining 10% of those infected in the near future or long-term factors are not clear, in the relapse of tuberculosis in some patients with tuberculin skin test showed a temporary non-reaction Sex. This article is based on the author’s laboratory on the results of human non-responsive research of tuberculosis to make a review. First, a correct understanding of tuberculosis Tuberculosis is one of the earliest discovered diseases, with the discovery of effective chemotherapy drugs, the study of tuberculosis has entered a downturn. In fact, half of the world’s population is tuberculin responders, indicating that they have been infected with Mycobacterium tuberculosis. It is estimated to appear every year