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目的研究振幅整合脑电图(aEEG)对于重症病毒性脑炎继发非惊厥型癫持续状态(NCSE)诊断的敏感度和特异度,探讨视频脑电图(VEEG)与aEEG结合在诊断NCSE中的临床意义。方法回顾性分析26例临床诊断为重症病毒性脑炎继发NCSE(NCSE组,经临床及脑电图判定符合NCSE)患儿的临床资料,另设对照组(22例,临床上存在意识障碍、自动症等表现,经判定不符合NCSE)。对两组病例进行脑电图检查及相关辅助检查。通过统计学分析对各项参数进行差异性分析。结果NCSE组在发作期及缓解期aEEG波幅差异有显著性(P<0.001),而对照组差异无显著性。以VEEG作为诊断标准,aEEG对于NCSE诊断的敏感度为100%,特异度为90.1%。结论对于重症病毒性脑炎继发NCSE的诊断,aEEG具有高敏感度、变化直观,易于快速解读等优势,对于尽早诊断及干预治疗有着重要意义。
Objective To study the sensitivity and specificity of aEEG for the diagnosis of non-convulsive epileptic seizure (NCSE) secondary to severe viral encephalitis, and to explore the feasibility and feasibility of combining video EEG (VEEG) with aEEG in the diagnosis of NCSE In the clinical significance. Methods A retrospective analysis of 26 cases of clinical diagnosis of severe viral encephalitis secondary NCSE (NCSE group, clinical and EEG determined NCSE) in children with clinical data, another set of control group (22 cases, the clinical presence of disturbance of consciousness , Autism and other performance, the decision does not meet the NCSE). Two groups of patients for EEG examination and related auxiliary examination. Through the statistical analysis of the various parameters of the difference analysis. Results There was a significant difference in the amplitude of aEEG between NCSE group and the control group (P <0.001), but there was no significant difference between NCSE group and control group. With VEEG as the diagnostic criteria, aEEG has a sensitivity of 100% for NCSE diagnosis and a specificity of 90.1%. Conclusions For the diagnosis of secondary NCSE of severe viral encephalitis, aEEG has the advantages of high sensitivity, intuitive change, easy to interpret quickly and so on, which is of great significance for early diagnosis and intervention treatment.