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目的探讨导致新生儿低血糖症的多种危险因素及监测血清胰岛素的意义。方法回顾分析2012年1月至2013年4月在我科收治的低血糖新生儿180例。结果早产儿组新生儿低血糖的发生率为9.86%,足月儿组新生儿低血糖的发生率为6.01%;早产儿血糖正常组与早产儿低血糖组的胰岛素水平比较差异无统计学意义(P>0.05)。母亲产前合并糖尿病组低血糖的发生率65.38%,其所生新生儿更容易发生新生儿低血糖症。母亲产前合并糖尿病的新生儿低血糖组更容易发生高胰岛素血症。合并窒息的新生儿更容易发生新生儿低血糖症。结论多种因素可造成新生儿低血糖症,对有发生低血糖高危因素的新生儿应常规监测血糖、血清胰岛素,识别高胰岛素血症,并尽早喂养或鼻饲,以减少新生儿低血糖的发生。
Objective To investigate the risk factors of neonatal hypoglycemia and the significance of monitoring serum insulin. Methods Retrospective analysis of 180 cases of hypoglycemia in our department from January 2012 to April 2013. Results The incidence of neonatal hypoglycemia in premature infants was 9.86%, the incidence of neonatal hypoglycemia in full-term infants was 6.01%, and there was no significant difference in insulin levels between premature infants with normal blood glucose and premature infants (P> 0.05). The incidence of hypoglycemia in the mother prenatal diabetes mellitus group was 65.38%, which was more likely to occur in infants with neonatal hypoglycemia. Mothers with prenatal diabetes mellitus were more likely to develop hyperinsulinemia. Neonatal hypoglycemia is more likely to occur in neonates with asphyxia. Conclusion A variety of factors can cause neonatal hypoglycemia, neonatal hypoglycemia should be routinely monitored for blood sugar, serum insulin, hyperinsulinemia, early feeding or nasal feeding to reduce the incidence of neonatal hypoglycemia .