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以往已作了很多用非生物材料修复气道壁部分缺损的实验,但效果都不甚理想。迄今临床上证明,仍以自体组织为最好的修复材料。某些病例,特别是气道缺损面积较大者,若用非生物性材料修复,有取材方便,造型容易、具有一定的硬度和性能稳定等优点,故必要时,也可考虑作为赝复材料;问题是非生物材料不具备粘膜衬里细菌易于侵入移植物中引起感染;在上皮形成过程中,由于瘢痕增生,常发生狭窄,故限制了它的使用。本文的研究目的是:1研究能否通过自体粘膜包囊技术——即用自体粘膜作衬里,非生物材料(Proplast)作支架,形成复合移植材料;②用这种材料带蒂复合移植修复气道缺损,并在实验过程中用内窥镜观察愈合过程;③在气
In the past, many experiments on repairing airway wall defects using non-biological materials have been made, but the results are not very satisfactory. So far clinically proven, still with autologous tissue as the best repair material. Some cases, especially the larger area of airway defects, if the use of non-biological material repair, a convenient, easy to shape, with a certain degree of hardness and stability of the advantages, it is necessary, it can also be considered as prosthetic material ; The problem is that non-biological materials do not have mucosal lining bacteria that can easily invade the graft and cause infection; during epithelialization, stenosis often occurs due to scarring, limiting its use. The purpose of this study is to: 1 study whether autologous mucosal cyst technique - that is, with autologous mucosa as lining, non-biological material (Proplast) as a scaffold to form a composite graft material; ② with this material pedicled compound graft repair gas Road defect, and in the course of the experiment using endoscopy to observe the healing process; ③ in the gas