论文部分内容阅读
抗生素对于眼科疾患具有良好的疗效,而且应用很广。在眼科方面的制剂有多种:如滴眼剂,眼用软膏剂,眼片剂(Lamellae)等。因近来药房调配眼膏剂的处方较多,故本文只就几种常用的抗生素眼用软膏剂加以介绍。一、青霉素眼膏(Oculentum Penicillini)青霉素的钙盐、钾盐或钠盐未完全精制时,为淡黄色或淡棕色的无定形粉末。但钠盐与钾盐亦可为结晶,结晶性粉末,颗粒或鳞片。均有潮解性。中国药典1953年版收载有青霉素眼膏。一般1 g软膏中含有青霉素1,000单位。青霉素可用钙盐、钾盐或钠盐。眼膏基质最好是用凡士林及羊毛脂(无水)的混合物,因其可促进药物的吸收,此较凡士林的稠度硬些,并具有润滑作用,故较之单独用凡士林为优。混合基质须经减菌并过滤后,再与青霉素研磨制备。方法见中国药典附录第7页“眼用软膏剂”项。但是也有不用上述混合物而用凡士林及液状石蜡的混合基质。例如英国药典1953年版的青霉素眼膏,处方如次.
Antibiotics have a good therapeutic effect on ophthalmic conditions and are widely used. There are many kinds of preparations for ophthalmology such as eye drops, ophthalmic ointments, eye drops (Lamellae) and the like. Due to the recent pharmacy deployment eye ointment prescription more, so this article only on several commonly used antibiotic ophthalmic ointment to be introduced. First, penicillin ointment (Oculentum Penicillini) Penicillin calcium, potassium or sodium salt is not fully refined, pale yellow or light brown amorphous powder. However, sodium and potassium salts can also be crystalline, crystalline powders, granules or scales. Both deliquescent. Chinese Pharmacopoeia 1953 version contains penicillin ointment. General 1 g ointment contains penicillin 1,000 units. Penicillins available calcium, potassium or sodium salt. Emery matrix is best to use a mixture of petroleum jelly and lanolin (anhydrous), because it can promote the absorption of drugs, the more rigid than Vaseline, and has a lubricating effect, it is better than alone with Vaseline. Mixed substrate to be reduced by bacteria and filtered, and then prepared with penicillin grinding. Methods see the Chinese Pharmacopoeia Appendix page 7 “ophthalmic ointment ” item. However, there is also a mixed matrix of petroleum jelly and liquid paraffin without using the above mixture. For example, the British Pharmacopoeia 1953 version of penicillin ointment, prescriptions as follows.