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婴儿期痉挛如无其他原因,应考虑暂时性甲状旁腺功能过低,此病在文献中报告甚少。其临床症状在出生后1～3周开始出现,婴儿表现易受刺激,特别是面部,对轻微刺激即可引起颤抖乃至抽搐。甲状旁腺功能过低的血清化学是低血钙、高血磷和正常碱性磷酸酶。当急性痉挛发生于1～3周间,钙、磷水平有相应的变化可确定诊断,否则应检查甲状旁腺素水平和环一单胺磷酸酶。发病机理可能是甲状旁腺通路障碍或机能低下,应密切注意母亲的潜伏性或未被发现的甲状旁腺功能亢进,划清暂时和持久的甲状旁腺功能低下只有通过观察过程。慢性甲状旁腺功能低下在维生素D治疗结
Infantile spasms should be considered for temporary hypothyroidism if there is no other cause. The disease has been reported poorly in the literature. The clinical symptoms in 1 to 3 weeks after birth began to appear, the baby vulnerable to irritation, especially the face, the slight stimulation can cause tremors and even convulsions. Serum chemistry for hypoparathyroidism is hypocalcemia, hyperphosphatemia, and normal alkaline phosphatase. When acute spasms occur in 1 to 3 weeks, there is a corresponding change in calcium and phosphorus levels to confirm the diagnosis, otherwise parathyroid hormone levels and monoamine phosphatase should be examined. Pathogenesis may be parathyroid access disorder or hypoparathyroidism, should pay close attention to the mother’s latent or undetected hyperparathyroidism, to identify temporary and lasting hypoparathyroidism only through the observation process. Chronic hypoparathyroidism at the vitamin D treatment node