1979年11月至1980年3月,作者收治4例一次吞服大量异菸肼而致急性中毒患者,均抢救成功。例1 尹××,女,16岁,学生,因突然反复抽搐3小时,而于1979年11月14日下午3时急诊入院。患者因精神刺激,入院前一日睡眠极差,次日诉头晕,家人未予注意,中午,突然发现患者四肢抽搐,口吐白沫(2～3分钟一次),非喷射性呕吐一次。急诊室拟诊“癫痫大发作”收入院。查体: November 1979 to March 1980, the author admitted to 4 cases of swallowing a large number of isoniazid caused acute poisoning patients were rescued. Example 1 Yin × ×, female, 16 years old, the student was admitted to the emergency department at 3:00 on November 14, 1979 due to a sudden and repeated convulsion for 3 hours. Patients due to mental stimulation, poor sleep on the day before admission, the next day complain of dizziness, the family did not pay attention, noon, suddenly found in patients with limbs twitching, foaming at the mouth (2 to 3 minutes), non-jet vomiting. Emergency room to be diagnosed “epileptic seizures” income homes. Physical examination: