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目的:探讨等离子经尿道前列腺电切(PKRP)和常规经尿道前列腺电切(TURP)对良性前列腺增生(BPH)患者生活质量的影响。方法:采取前瞻性随机对照的方法将105名需要手术治疗的BPH患者随机分成二组:即TURP组51例,PKRP组54例。使用IPSS、QOL和WHOQOL-BREF量表,分别在术前、术后第1、6和12个月对患者的LUTS和生活质量进行评估。结果:TURP组和PKRP组患者的生活质量在术后6个月得到明显改善。TURP组术后第6个月的IPSS、QOL和WHOQOL-BREF评分分别为10.4±2.6,1.7±0.6和55.1±7.4,术后第12个月的IPSS、QOL和WHOQOL-BREF评分分别为11.4±2.6,1.7±0.5和55.2±6.9,均比术前(21.5±5.3,5.3±0.9和52.4±7.0)有明显改善。PKRP组术后第6个月的IPSS、QOL和WHOQOL-BREF评分分别为9.8±2.4,1.5±0.4和57.9±8.1,术后第12个月的IPSS、QOL和WHOQOL-BREF评分分别为10.6±2.2,1.7±0.5和56.3±6.2,均比术前(21.3±6.1,5.2±1.0和55.0±8.8)有明显改善。结论:TURP和PKRP术后第6个月患者的生活质量得到持续改善,WHO-QOL-BREF可以作为评价TURP和PKRP对BPH患者生活质量影响的可靠测量工具。
Objective: To investigate the effect of plasma transurethral resection of prostate (PKRP) and conventional transurethral resection of prostate (TURP) on the quality of life of patients with benign prostatic hyperplasia (BPH). Methods: A total of 105 BPH patients undergoing surgical treatment were randomly divided into two groups according to a prospective randomized controlled trial: 51 in the TURP group and 54 in the PKRP group. Patients’ LUTS and quality of life were assessed preoperatively, 1, 6, and 12 months after surgery using the IPSS, QOL, and WHOQOL-BREF scales, respectively. Results: The quality of life of patients in the TURP and PKRP groups improved significantly at 6 months after surgery. The IPSS, QOL and WHOQOL-BREF scores of the TURP group were 10.4 ± 2.6, 1.7 ± 0.6 and 55.1 ± 7.4 respectively at the 6th month after surgery. The IPSS, QOL and WHOQOL-BREF scores of the 12th month after surgery were 11.4 ± 2.6, 1.7 ± 0.5 and 55.2 ± 6.9, which were significantly improved compared with the preoperative (21.5 ± 5.3,5.3 ± 0.9 and 52.4 ± 7.0). The IPSS, QOL and WHOQOL-BREF scores of the PKRP group were 9.8 ± 2.4, 1.5 ± 0.4 and 57.9 ± 8.1 respectively at the 6th month after surgery. The scores of IPSS, QOL and WHOQOL-BREF at the 12th month after surgery were 10.6 ± 2.2, 1.7 ± 0.5 and 56.3 ± 6.2, which were significantly improved compared with the preoperative (21.3 ± 6.1, 5.2 ± 1.0 and 55.0 ± 8.8). CONCLUSIONS: The quality of life in patients at 6 months after TURP and PKRP has been consistently improved, and WHO-QOL-BREF can be used as a reliable measure of the impact of TURP and PKRP on the quality of life in BPH patients.