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患者男性,36岁。1995年5月13日因发热、咽痛,口服复方新诺明(COSMZ)2片,约2小时后感口唇麻痒,5小时后双眼胀痛,傍晚续服COSMZ2片,次日早晨双眼畏光、流泪,视物模糊,口腔粘膜烧灼样疼痛而来院急诊。无其他药物接触史,既往无药物过敏史。体检:体温38.5℃,全身无皮疹及出血点,心肺正常,腹无特殊。眼科:远视力右眼0.6,左眼0.7,双眼结膜混合充血,角膜实质层由周边到中央呈细点状灰白色混浊,荧光素染
Male patient, 36 years old. May 13, 1995 due to fever, sore throat, oral compound cotrimoxazole (COSMZ) 2, about 2 hours after the mouth itching sensation, eyes pain after 5 hours, COSMZ2 film continued in the evening, the morning of the next morning Light, tears, blurred vision, oral mucosal burning pain from hospital emergency. No other drug exposure history, no past history of drug allergy. Physical examination: body temperature 38.5 ℃, body rash and bleeding, normal heart and lungs, abdomen no special. Ophthalmology: far vision of the right eye 0.6, left eye 0.7, conjunctival mixed congestion, corneal parenchyma from the periphery to the center was fine gray turbidity, fluorescein staining