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目的评价经导管介入治疗动脉导管未闭(PDA)的有效性及安全性。方法全组120例患者,年龄(23.5±16.0)岁。降主动脉造影确定动脉导管的形态及最窄径,选择合适的封堵器。术前及术后1,3及6个月行超声心动图检查。结果 PDA最窄径1.5～14.0mm,平均(5.7±3.0)mm。封堵成功率99%。术后即刻残余分流38%,1个月时无残余分流。9例重度肺动脉高压患者术前肺动脉收缩压83～155mmHg(1mmHg=0.133kPa),平均(108.6±21.6)mmHg,术后1个月时降至36～92mmHg,平均(54.1±16.6)mmHg(P<0.01)。无严重并发症发生。结论在严格掌握适应证的前提下,经导管介入治疗PDA安全有效。
Objective To evaluate the effectiveness and safety of transcatheter catheterization of patent ductus arteriosus (PDA). Methods The whole group of 120 patients, age (23.5 ± 16.0) years old. Descending aorta arterial catheterization to determine the shape and narrowest diameter, select the appropriate occluder. Echocardiography was performed preoperatively and 1, 3 and 6 months after surgery. Results PDA narrowest diameter 1.5 ~ 14.0mm, with an average (5.7 ± 3.0) mm. Blocking success rate of 99%. Postoperative residual shunt 38%, 1 month without residual shunt. Preoperative pulmonary artery systolic pressure was 83 ~ 155mmHg (1mmHg = 0.133kPa) in 9 patients with severe pulmonary hypertension, with an average of (108.6 ± 21.6) mmHg and decreased to 36 ~ 92mmHg at 1 month after operation, with an average of (54.1 ± 16.6) mmHg <0.01). No serious complications occurred. Conclusion Under the strict control of indications, transcatheter treatment of PDA is safe and effective.