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铁在人体中含量约为4 g,主要存在两类功能性结构中。一种含量占70%左右,以红细胞中的血红蛋白、肌纤维中的肌红蛋白的形式存在;另一种含量占30%,以铁蛋白或含铁血黄素等贮存铁的形式贮存于骨髓和肝、脾中。铁是线粒体呼吸链和核糖核酸氧化酶及还原酶的组成成分,在体内氧化-还原反应中起着重要作用。而肝脏是其贮存和代谢的重要器官,因此,肝脏铁代谢异常与肝脏疾病密切相关。通过
Iron in the human body is about 4 g, mainly in two types of functional structures. A content of about 70% of the hemoglobin in red blood cells, muscle fibers in the form of myoglobin exists; the other content of 30%, ferritin or hemosiderin storage iron in the form of stored in the bone marrow and liver , Spleen. Iron is a component of the mitochondrial respiratory chain and ribonucleic acid oxidase and reductase and plays an important role in the oxidation-reduction reaction in vivo. The liver is an important organ for its storage and metabolism. Therefore, abnormal liver iron metabolism is closely related to liver diseases. by