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作者收集了由Lukes等确诊的33例免疫母细胞肉瘤病例,复习了临床资料,以进一步从临床上描述此种疾患。文中扼要叙述了诊断免疫母细胞肉瘤的形态学标准:单一形态的大细胞增殖,胞核比反应性组织细胞的大或等长。核膜增厚、规则,微细分布的淡染染色质,有二或三个明显的核仁。胞浆丰富,苏木素伊红染色为双染性,甲基绿派若宁染色为强嗜派洛宁性。常出现浆细胞样特征。主要临床表现: 年龄和性别:男性19例,女性14例。诊断时平均年龄为56岁,男性平均年龄为49岁(年龄范围为21-69岁),女性平均年龄为65岁(年龄范围为17-85岁)。既往史:10例(30%)以往有免疫异常或淋巴增殖性恶性疾患。前者包括粥样泻,慢性荨麻诊,哮喘,
The authors collected 33 cases of immunoblastic sarcoma confirmed by Lukes et al and reviewed the clinical data to further describe the disease clinically. The article briefly describes the diagnosis of immunoblastic sarcoma morphological criteria: a single form of large cell proliferation, nuclear than reactive tissue cells of the same or equal length. Nuclear membrane thickening, regular, finely distributed lightly stained chromatin, with two or three distinct nucleoli. Cytoplasm is abundant, hematoxylin and eosin are double-stained, and methyl-chlorophenanone is strongly dispatched to send lupine. Plasmacytoid features often appear. The main clinical manifestations: age and gender: 19 males and 14 females. The average age at diagnosis was 56 years. The average age of men was 49 years (range, 21-69 years) and the average age of women was 65 years (range, 17-85 years). Past history: In the past, 10 patients (30%) had abnormal immune or lymphoproliferative malignancies. The former includes atherosclerosis, chronic nettle diagnosis, asthma,