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妇女妊娠时,血液系统有许多改变,这是妊娠机体为了适应新形成的母体胎儿系统需要而发生的变化。对母体有保护作用,却也能导致疾病。妊娠中的高凝状态妊娠期血浆中凝血因子有显著改变。这可能本是为胎盘与母体分离止血所需的一种生理机能。妊娠期除Ⅺ和Ⅻ因子外,所有血浆凝血因子都增高,这些因子约在妊娠6个月时开始升高。纤维蛋白原,Ⅶ、Ⅹ、Ⅷ因子在妊娠8个月左右升至妊娠前的2倍,第三产程中Ⅷ因子水平最高。它们在分娩6周后都降至正常水平。纤维蛋白溶解系统也有显著变化。血浆中纤溶酶原浓度升高,而其活化因子活性下降。在妊娠3个月时,纤维蛋白溶解活性开始下降,在胎盘娩出后15mim,纤维蛋白溶解活性立即恢复正常。
There are many changes in the blood system of a woman during pregnancy, which is a change in the pregnancy that takes into account the needs of the newly formed maternal fetal system. Have a protective effect on the mother, but can also lead to disease. Hypercoagulable state during pregnancy in plasma coagulation factors have significant changes. This may have been the physiological function required for the placenta to separate from the mother to stop bleeding. In addition to Ⅺ and 妊 factors during pregnancy, all plasma clotting factors are increased, these factors about 6 months of pregnancy began to rise. Fibrinogen, Ⅶ, Ⅹ, Ⅷ factor in pregnancy about 8 months rose to 2 times before pregnancy, the third stage of the highest factor Ⅷ level. They all returned to normal levels 6 weeks after delivery. There are also significant changes in the fibrinolytic system. Plasma plasminogen concentration increased, while its activity of activated factor decreased. At 3 months of gestation, fibrinolytic activity began to decline, and 15 mim after delivery of the placenta, fibrolytic activity immediately returned to normal.