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目的：观察细胞毒化疗对急性白血病细胞原位凋亡的影响。方法：应用 DNA原位末端标记（ ISEL）方法，检测初发及经治的 31例急性白血病骨髓塑包切片内细胞原位凋亡数量及特征，以 10例缺铁性贫血为对照，并进行自身组间对照。结果：初治 AL凋亡减少，与对照组相比有显著差异（ P
Objective: To observe the effect of cytotoxic chemotherapy on in situ apoptosis of acute leukemia cells. Methods: The number and characteristics of in situ cell apoptosis in 31 cases of primary leukemia and bone marrow smears of primary leukemia were detected by DNA in situ (ISEL) method. Ten cases of iron deficiency anemia were used as control Self between groups control. Results: The apoptotic rate of AL in newly diagnosed group decreased significantly compared with control group (P <0.01)