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本文报道胸内结节病4例结素试验为强阳性的病人,提出此结果与国内结节病的诊断标准存在差异,阐述了发病机理的初步设想,以期为结节病提供新的诊断依据。结素反应是判断机体有无迟发超敏反应(IV型超敏反应)能力的皮肤试验,是由T细胞介导的反映宿主细胞免疫功能的试验。在胞内菌感染(如结核杆菌、麻风杆菌等)机体可同时产生细胞免疫和迟发超敏反应,而且人群中存在明显个体差异性。结节病人的病因尚不清楚,其发病与结素反应强弱有无内在关系仍需进一步探讨,希望读者对此给予关注或讨论。
This article reports 4 cases of intrathoracic sarcoidosis test for patients with strong positive, put forward the results and domestic diagnostic criteria for sarcoidosis are different, described the initial idea of the pathogenesis in order to provide a new diagnosis of sarcoidosis . Cortisin response is a skin test to determine the ability of the body to have delayed hypersensitivity (Type IV hypersensitivity) and is a test mediated by T cells to reflect host cell immune function. In the intracellular bacteria infection (such as Mycobacterium tuberculosis, leprosy, etc.) body can simultaneously produce cellular immunity and delayed hypersensitivity, and the population there is a clear individual differences. The etiology of patients with nodules is not yet clear, its incidence and non-intrinsic relationship between the outcome of the tuberculosis still need to be further explored, I hope readers to give attention or discussion.