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为了解农药对家蚕的慢性毒性影响,探索建立我国农药对家蚕的慢性毒性试验及评价方法体系,以3种不同类型的代表性杀虫剂高效氯氟氰菊酯、甲氨基阿维菌素苯甲酸盐和氟铃脲为代表药剂,针对家蚕进行了给药阶段、给药剂量及评价指标的系统研究。结果表明:慢性毒性试验中的给药阶段以2~3龄期为宜;给药剂量可为其急性毒性96 h-LC50值的1/50、1/100、1/200、1/400和1/800;主要评价指标应为结茧率。
In order to understand the chronic toxicity of pesticides to silkworm and explore the establishment of China’s pesticides on silkworm chronic toxicity test and evaluation system, with three different types of representative insecticides lambda-cyhalothrin, emamectin benzoate Formate and hexaflumuron as representative agents, the silkworm administered for the stage, dose and evaluation indicators of the system. The results showed that: the chronic toxicity test in the period of 2-3 days is appropriate; the dose can be acute toxicity 96 h-LC50 value of 1 / 50,1 / 100,1 / 200,1 / 400 and 1/800; the main evaluation index should be the cocoon rate.