化疗是肿瘤治疗的重要手段,目前现有的化疗药物普遍选择性不高,在杀伤肿瘤细胞的同时也可能损害体内某些类型的正常细胞,常出现较明显的毒副反应,因此肿瘤靶向治疗已成为提高治疗效果的一条重要途径。而肿瘤相关抗原及其相应的单克隆抗体(monoclone antibody,mAb)的出现,使得制备一种具有选择性抗肿瘤作用的药物的研究有了很大的发展。 Chemotherapy is an important means of tumor treatment. Currently, the existing chemotherapeutic drugs are generally not highly selective. While killing tumor cells, they may also damage some types of normal cells in the body and often cause obvious toxic and side reactions. Therefore, tumor targeting Treatment has become an important way to improve the therapeutic effect. The emergence of tumor-associated antigens and their corresponding monoclonal antibodies (mAbs) has led to a great development in the research of the preparation of a selective antitumor drug.