耐多药结核病是指结核菌至少同时对异烟肼、利福平两种抗结核药物耐药。自20世纪90年代以来,全球结核病疫情回升,导致结核病疫情升高的诸多因素中,耐多药结核病是主要原因之一。2008年WHO报告显示,2006年全球超过50万耐多药结核病例,2000年全国结核病流行病学调查结果显示我国初始耐多药率和获得耐多药率分别高达7.6%和17.1%,耐多药结核病已成为一个严重的公共卫生问题。目前,耐多药结核病的治疗仍以西医化学治疗为主,但存在疗程长、治疗费用高、不良反应高,严重影响其治疗效果及治疗方案的推广。中医药治疗肺结核有悠久的历史,许多临床试验显示中医药具有提高患者疗效、减轻化疗副反应等作用,然 Multidrug-resistant tuberculosis means that TB is resistant to at least two isoniazid and rifampicin-resistant anti-TB drugs. Among the many factors that have contributed to the rising tuberculosis epidemic since the 1990s, the global tuberculosis epidemic has risen, and MDR-TB is one of the major causes. According to the 2008 WHO report, over 500,000 MDR-TB cases in the world in 2006 and the national epidemiological survey of tuberculosis in 2000 showed that the initial MDR-resistant rate and the multi-drug resistant rate were as high as 7.6% and 17.1% respectively in China, Tuberculosis has become a serious public health problem. At present, the treatment of MDR-TB is still dominated by western medicine, but there are long courses of treatment, high cost of treatment and high adverse reactions, which seriously affect the treatment effect and the promotion of treatment programs. Chinese medicine treatment of tuberculosis has a long history, many clinical trials show that traditional Chinese medicine has the effect of improving patient efficacy and reduce the side effects of chemotherapy, etc. However