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氧氟沙星是８０年代末最新采用的喹啉类药。据报道氧氟沙星滴耳液较传统使用的抗生素或抗生素一类固醇滴耳液对活动期慢性化脓性中耳炎（ＣＳＯＭ）治疗有较好效果。为此该文对氧氟沙星和新霉素一多粘菌素Ｂ－氢化可的松滴耳液对活动期ＣＳＯＭ的疗效、细菌杀灭力和耳毒性进行
Ofloxacin is the latest quinoline used in the late 1980s. It has been reported that ofloxacin ear drops than the traditional use of antibiotics or antibiotics steroid ear drops on active chronic suppurative otitis media (CSOM) treatment has a good effect. To this end the efficacy of ofloxacin and neomycin-polymyxin B-hydrocortisone ear drops on active CSOM, bacterial killing and ototoxicity