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目的探讨嗜酸性膀胱炎的临床表现、病理特点和诊治方法。方法对嗜酸性膀胱炎2例进行临床分析并结合文献复习,从临床表现、病理特点和诊治方法及疗效等方面总结。例1,男,63岁,主要表现为无明显诱因出现间断性肉眼血尿,伴尿频、尿急、排尿困难和腹痛,无明显过敏史,膀胱镜检查示膀胱底部有5 cm×3 cm范围增生隆起,高出黏膜0.2~0.4 cm。例2,女,42岁,无明显诱因出现尿频、尿急、排尿困难和耻骨上疼痛并伴间断血尿,无明显过敏史,膀胱镜检查见膀胱底及膀胱颈部菜花样肿瘤病变,大小约4 cm×3 cm×2 cm,高出黏膜0.3~0.4 cm。B超、CT及IVU等影像学检查2例均表现为膀胱壁增厚和占位性病变。2例均行经尿道病变电切术并辅以皮质激素、抗生素治疗。结果2例患者术后病理均为嗜酸性膀胱炎。术后随访6个月,排尿异常症状消失,B超、CT及IVU等影像学及膀胱镜检查未见膀胱占位性病变。结论嗜酸性膀胱炎临床少见,易误诊为膀胱肿瘤,膀胱镜检查与组织活检和切除组织的病理检查是诊断的必要步骤,治疗方法包括经尿道膀胱病变切除术并辅以非特异性的药物治疗。
Objective To investigate the clinical manifestations, pathological features and diagnosis and treatment of eosinophilic cystitis. Methods The clinical analysis of 2 cases of eosinophilic cystitis combined with literature review, from the clinical manifestations, pathological features and diagnosis and treatment methods and efficacy summary. Example 1, male, 63 years old, showed no obvious predisposition of intermittent gross hematuria with frequent urination, urgency, dysuria and abdominal pain, no obvious history of allergy, cystoscopy showed a 5 cm × 3 cm range of the bottom of the bladder hyperplasia Uplift, higher than the mucosa 0.2 ~ 0.4 cm. Case 2, female, 42 years old, no obvious incentive to urinary frequency, urgency, dysuria and suprapubic pain with intermittent hematuria, no obvious history of allergies, cystoscopy and cyst bladder bladder carapace tumor lesions, size 4 cm × 3 cm × 2 cm, higher than the mucosa 0.3 ~ 0.4 cm. B ultrasound, CT and IVU other imaging studies showed 2 cases of bladder wall thickening and space-occupying lesions. 2 cases underwent transurethral resection combined with corticosteroids, antibiotics. Results The pathology of the two patients were all eosinophilic cystitis. The patients were followed up for 6 months. The abnormal urination symptoms disappeared. Bladder space-occupying lesions were not seen in the imaging and cystoscopy such as B-ultrasound, CT and IVU. Conclusions Eosinophilic cystitis is a rare clinical and easily misdiagnosed as bladder tumor. Cystoscopy and biopsy and pathological examination of excised tissue are necessary steps for diagnosis. The treatment includes transurethral resection of bladder disease with nonspecific drug treatment.