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目的观察灯盏花素联合阿托伐他汀治疗不稳定型心绞痛的疗效。方法选取本院2006年11月至2008年11月100例不稳定心绞痛患者随机分为对照组(50例)和治疗组(50例),两组除应用常规的心绞痛治疗以外,对照组加用阿托伐他汀,治疗组合用阿托伐他汀和注射用灯盏花素,均连续使用10 d。结果治疗组显效31例(62%)、有效17例(34%)、无效2例(4%),总有效率为96%。对照组50例中显效19例(38%)、有效20例(40%)、无效11例(22%),总有效率为78%。治疗组的总有效率显著高于对照组(P<0.05)。在心电图改善方面,治疗组显效14例、有效27例、无效9例,总有效率82.0%,对照组显效9例、有效22例、无效19例,总有效率62.0%,治疗组明显优于对照组(P<0.05)。结论阿托伐他汀联合注射用灯盏花素治疗不稳定型心绞痛有良好的疗效。
Objective To observe the efficacy of breviscapine combined with atorvastatin in the treatment of unstable angina pectoris. Methods A total of 100 patients with unstable angina pectoris from November 2006 to November 2008 in our hospital were randomly divided into control group (50 cases) and treatment group (50 cases). In addition to conventional angina pectoris treatment, Atorvastatin, combination therapy with atorvastatin and breviscapine for injection, were used continuously for 10 days. Results The treatment group was markedly effective in 31 cases (62%), effective in 17 cases (34%), ineffective in 2 cases (4%), the total effective rate was 96%. The control group, 50 cases showed effective in 19 cases (38%), effective in 20 cases (40%), ineffective in 11 cases (22%), the total effective rate was 78%. The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). In the electrocardiogram improvement, the treatment group markedly effective in 14 cases, effective in 27 cases, ineffective in 9 cases, the total effective rate was 82.0% in the control group, 9 cases markedly effective in 22 cases, ineffective in 19 cases, the total effective rate was 62.0%, the treatment group was significantly better than Control group (P <0.05). Conclusions Atorvastatin combined with breviscapine injection has a good effect on unstable angina pectoris.