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小鼠SRS腹水瘤是本校病理生理学教研室于1971年建立的瘤株,在不同品系小鼠中均能100%移植发病,瘤细胞超薄切片的超微结构中观察到A 型和C 型病毒颗粒,并已证明具有致白血病活性.1984年采用有限稀释微板培养法,对SRS-82细胞进行连续克隆化,建成一个SAC 克隆系列.现报道该系列中SAC-ⅡB2和SAC-ⅡC3克隆细胞株的生物学和免疫学研究.在克隆细胞分瓶传递后的观察中,发现
Mouse SRS ascites tumor is a tumor strain established in the Department of Pathology and Physiology of our school in 1971. It can be transplanted 100% in different strains of mice. A-type and C-type virus particles were observed in the ultrastructure of tumor cells. , And has proved to have leukemia activity. In 1984, the limited dilution microplate culture method, the continuous cloning of SRS-82 cells, to build a SAC clone series. It is reported that the series of SAC-IIB2 and SAC-IIC3 clone cell lines Biological and immunological studies. Found in observations after transfection of cloned cells