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近几年来,随氯丙嗪广泛应用其不良反应不断出现,但一些临床工作者都没引起足够认识。本文查阅有关文献,对氯丙嗪临床应用中的副作用以及处理原则予以介绍如下: 一、对锥体外系的影响:吩嗪类药物引起锥体外系的副作用,其中以氯丙嗪为主要代表性药物,发病率约占30％。常表现为:震颤性麻痹、静坐不能、急性肌痉挛和迟发性运动障碍的锥体外系综合征。临床体征为:颈抵抗、斜、后仰、
In recent years, with the widespread use of chlorpromazine its adverse reactions continue to occur, but some clinicians did not cause enough knowledge. This article access to the literature on the clinical use of chlorpromazine side effects and principles of treatment are described as follows: First, the extrapyramidal effects: phenazine drugs cause extrapyramidal side effects, of which chlorpromazine as the main representative Drugs, the incidence of about 30%. Often manifested as: tremor paralysis, can not sit, acute muscular spasm and tardive dyskinesia extrapyramidal syndrome. Clinical signs: neck resistance, oblique, backward,