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目的:对国产离子型对比剂泛影葡胺与进口非离子型对比剂优维显在肝细胞癌(HCC)患者螺旋 CT增强扫描中效果比较。方法:对198例HCC患者进行肝脏螺旋CT(SCT)三期增强扫描,其中105例选用60%泛影葡胺(含 I 292 g/L),93例选用优维显(含I300 g/L)。观察 2种对比剂的不良反应及 CT影像质量。结果:泛影葡胺组中有3例(2．9%)出现不良反应,其中轻度2例(1．9%),中度1例(1．0%);优维显组有1 例(1．1%)出现轻度不良反应。2组均无重度不良反应与死亡发生(P＞0．05)。影像质量2组近似。结论:国产离子型对比剂对于无高危因素的人群安全可靠,并可获得质量满意的螺旋CT增强图像,是诊断HCC的有效对比剂。
OBJECTIVE: To compare the effects of domestic ionotropic contrast agent meglumine diatrizoate and imported non-ionic contrast agent Euveo in the spiral CT enhanced scanning of patients with hepatocellular carcinoma (HCC). Methods: A total of 198 patients with HCC underwent enhanced spiral CT (SCT) three-phase scanning. Among them, 105 were selected with 60% diatrizoate (I 292 g / L) ). Adverse reactions of two contrast agents and CT image quality were observed. Results: Three patients (2.9%) in the meglumine diatrizoate group had adverse reactions, of which 2 were mild (1.9%) and 1 (1.0%) moderate, and 1 Cases (1.1%) showed mild adverse reactions. No severe adverse reactions and death occurred in both groups (P> 0.05). Image quality 2 groups approximation. CONCLUSION: Domestic ionotropic contrast agents are safe and reliable for people without risk factors and can obtain satisfactory images of helical CT. It is an effective contrast agent for diagnosing HCC.