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目的分析小儿泌尿系感染致病菌及药敏情况。方法回顾性分析2008-2010年间56例中段尿培养阳性的住院患儿的临床资料。结果共检出菌株88株,泌尿系感染以革兰阴性菌为主,在泌尿系感染中占前三位的细菌为埃希菌属、肠球菌属和克雷伯菌属。体外药敏试验显示,细菌耐药率高,尤以氨苄青霉素和一至三代头孢菌素类药物突出;埃希菌和克雷伯菌的ESBLs检出率分别为33%和40%。结论小儿泌尿系感染致病菌以G-杆菌为主,但病原菌耐药情况比较严重。应及时了解泌尿系感染流行病学资料,以指导临床正确用药。
Objective To analyze pediatric urinary tract infection pathogens and drug susceptibility. Methods Retrospective analysis of 56 cases of mid-urine urinary tract-positive in-hospital clinical data in 2008-2010. Results A total of 88 isolates were detected. Gram-negative bacteria were predominant in urinary tract infection. The top three bacteria in urinary tract infection were Escherichia, Enterococcus and Klebsiella. In vitro susceptibility tests showed that the bacterial resistance rate was high, especially ampicillin and first to third generation cephalosporins; ESBLs detection rates of Escherichia coli and Klebsiella were 33% and 40% respectively. Conclusion The main pathogens of urinary tract infection in children are G-bacilli, but the pathogens are more resistant. Should keep abreast of urinary tract infection epidemiological data to guide clinical correct medication.