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目的观察小儿豉翘清热颗粒联合抗病毒药治疗手足口病的临床疗效、毒副作用。方法将141例临床确诊为手足口病患儿随机分为两组,治疗组76例用小儿豉翘清热颗粒联合病毒唑,附以维生素C或B族维生素,对照组65例用单用病毒唑,附以维生素C或B族维生素。结果治疗组显效率79%,有效率25%,对照组显效率55.6%,有效率41.7%,两组治疗比较差异有统计学意义(P<0.01),且治疗组热程、皮疹消退时间均明显缩短。结论小儿豉翘清热颗粒治疗手足口病有良好的临床疗效,副作用轻,值得临床应用。
Objective To observe the clinical efficacy and side effects of Xiaoer Qiaoqiao Qingre granules combined with antivirals in the treatment of hand, foot and mouth disease. Methods 141 cases of clinically diagnosed hand-foot-mouth disease were randomly divided into two groups. The treatment group, 76 cases of children with Qiqiao Qingre granules combined with ribavirin, with vitamin C or B vitamins, the control group, 65 cases with single ribavirin , With vitamin C or B vitamins. Results In the treatment group, the effective rate was 79% and the effective rate was 25%. The effective rate in the control group was 55.6% and the effective rate was 41.7%. The differences between the two groups were statistically significant (P <0.01) Significantly shorter. Conclusion The treatment of hand-foot-mouth disease in children with Qiqiaoqingre granules has good clinical curative effect with less side effects and is worthy of clinical application.