It is known (for example see [2]) that the maximum genus of a graph is mainly determined by the Betti deficiency of the graph. In this paper, the authors establish an upper bound on the Betti deficiency in terms of the independence number as well as the girth of a graph, and thus use the formulation in [2] to translate this result to lower bound on the maximum genus.Meantime it is shown that both of the bounds are best possible.