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目的分析重度子痫前期合并低蛋白血症对妊娠结局的影响。方法分析330例重度子痫前期的临床资料,根据血清白蛋白测定结果将患者情况分为低蛋白血症组(A组178例)和正常血清白蛋白组(B组152例)。通过比较两组发病时间、入院治疗时间、终止妊娠时间、有无合并症、新生儿出生体重、肺间质水肿、胸腔积液及脑水肿、胎盘早剥发病情况,评价低蛋白血症对重度子痫前期患者妊娠结局的影响。结果低蛋白血症组新生儿出生体重明显低于正常血清白蛋白组,随之新生儿窒息发生率高,差异具有统计学意义(P<0.05)。低蛋白血症组孕产妇并发症发生率升高,肺间质水肿、胸腔积液及脑水肿发病率高于正常血清白蛋白组,差异具有统计学意义(P<0.05)。结论重度子痫前期并发低蛋白血症患者并发症多,临床应密切监测病情,适时终止妊娠。
Objective To analyze the effect of severe preeclampsia with hypoproteinemia on pregnancy outcome. Methods The clinical data of 330 patients with severe preeclampsia were analyzed. The patients were divided into hypoalbuminemia group (178 cases) and normal serum albumin group (152 cases in group B) according to the results of serum albumin determination. By comparing the onset time of the two groups, admission treatment time, termination of pregnancy, with or without complications, birth weight, pulmonary interstitial edema, pleural effusion and cerebral edema, placental abruption incidence, evaluation of hypoproteinemia to severe Effect of pregnancy outcome in patients with preeclampsia. Results The neonatal birth weight in hypoproteinemia group was significantly lower than that in normal serum albumin group, followed by high neonatal asphyxia (P <0.05). Hypoproteinemia group maternal complications increased incidence of interstitial edema, pleural effusion and cerebral edema incidence was higher than normal serum albumin, the difference was statistically significant (P <0.05). Conclusions There are many complications in patients with severe preeclampsia and hypoproteinemia. Clinically, the condition should be closely monitored and the pregnancy terminated.