目的:探讨新型非甾体滴眼液0.1%溴芬酸钠水合物滴眼液在翼状胬肉术后的早期镇痛效果及对减轻术后眼部刺激症状的疗效及安全性。方法:选择2016年1月至2017年12月浙江省苍南县人民医院（温州医科大学附属苍南医院）诊治的100例（112只眼）翼状胬肉患者，根据就诊顺序，按照奇偶数随机分为观察组和对照组，每组50例，两组患者术前和术后7 d均常规使用妥布霉素滴眼液（4次/d），观察组加用0.1%溴芬酸钠水合物滴眼液（2次/d），对照组不使用任何非甾体抗炎药。比较两组术后6、8、24、48、72 h疼痛评分和角膜创面的愈合情况。结果:观察组术后6、8、24、48、72 h疼痛评分均小于对照组[（0.96 ± 0.13）分比（2.21 ± 0.07）分、（0.90 ± 0.05）分比（1.71 ± 0.30）分、（0.71 ± 0.07）分比（1.54 ± 0.09）分、（0.51 ± 0.04）分比（1.31 ± 0.10）分、（0.21 ± 0.02）分比（0.80 ± 0.10）分]，差异有统计学意义（n P0.05）。术后7 d两组角膜愈合率均为100.0%（57/57、55/55）。n 结论:翼状胬肉患者术前和术后应用0.1%溴芬酸钠滴眼液，能安全有效地减轻术后早期疼痛。“,”Objective:To evaluate the early analgesic effect of new non-steroidal anti-inflammatory drugs 0.1% bromofenac sodium hydrate eye drops in pterygium surgery and the efficacy and safety on relieving the irritative symptoms.Methods:One hundred patients (112 eyes) with pterygium who were treated in Cangnan People′s Hospital (Cangnan Hospital Affiliated of Wenzhou Medical University) from January 2016 to September 2017 were selected and divided into observation group and control group by the hospital sequence, with 50 patients in each group. Before operation and 7 d after operation, the patients in two group were given topical tobramycin eye drops (4 times a day), and the patients in observation group were given 0.1% bromofenac sodium hydrate eye drops twice a day on the base of tobramycin eye drops. The patients were investigated early after operation and the pain scores of the two groups were compared 6, 8, 24, 48 and 72 h after operation.The corneal epithelial healing was compared too.Results:The pain scores in observation group 6, 8, 24, 48 and 72 h after operation were significantly lower than that in control group [(0.96 ± 0.13) scores vs. (2.21 ± 0.07) scores, (0.90 ± 0.05)scores vs. (1.71 ± 0.30) scores, (0.71 ± 0.07) scores vs.(1.54 ± 0.09) scores, (0.51 ± 0.04) scores vs. (1.31 ± 0.10) scores, (0.21 ± 0.02) scores vs. (0.80 ± 0.1) scores], and the differences were statistically significant (n P<0.05). The corneal wound healing rate of the two groups 2 or 3 d after operaion had no significant differences and the corneal wound healing rate 7 d after operaion was 100.0% (57/57, 55/55) in two groups.n Conclusions:In pterygium surgery patients, using 0.1% bromfenac sodium hydrate drops before and after operation to relieve pain is valid, and can effectively relieve early postoperative pain.