作者报告4例弥漫性红斑性狼疮患者(均为年青女性),伴发头痛,视乳头水肿和颅内压增高(其中1例腰穿压力高达460毫米水柱),但无局灶性神经体征。全部病例脑脊液蛋白和细胞正常,经应用中等剂量的激素治疗,颅内压迅速下降,视乳头水肿亦迅速消退。有些红斑性狼疮伴发颅内压增高的患者,经激素治疗后,颅内压迅速下降,但肾功能并未改善,因此作者认为由于肾脏疾患所致的代谢障碍与颅内压增高 The authors reported 4 patients with diffuse lupus erythematosus (all young women) with headache, papilledema and increased intracranial pressure (1 patient had a lumbar pressure of 460 mm H2O) but no focal neurological signs. Cerebrospinal fluid in all cases of normal protein and cells, the application of moderate doses of hormone therapy, intracranial pressure decreased rapidly, papilledema also rapidly subsided. Some patients with lupus erythematosus associated with increased intracranial pressure, hormone therapy, the rapid decline in intracranial pressure, but renal function did not improve, so the author believes that due to renal disorders caused by metabolic disorders and increased intracranial pressure