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目的探讨紫杉醇联合顺铂治疗晚期食道癌的临床效果。方法选取我院2008年至1月至2012年12月114例食晚期道癌患者,将其随机分为研究组和对照组,其中对照组应用5-氟尿嘧啶联合顺铂给予治疗;研究组应用紫杉醇联合顺铂给予治疗,比较两组患者临床治疗效果以及不良反应。结果研究组患者和对照组比较临床治疗效果更加显著,差异存在统计学意义(P<0.05);两组患者均未出现严重并发症,差异不存在统计学意义(P>0.05)。结论紫杉醇联合顺铂治疗晚期食道癌,能够增加患者存活率,促使生存时间延长,没有较严重并发症出现。
Objective To investigate the clinical effect of paclitaxel combined with cisplatin in the treatment of advanced esophageal cancer. Methods A total of 114 patients with advanced carcinoma of the passage of life in our hospital from January 2008 to January 2012 were selected and randomly divided into study group and control group. The control group was treated with 5-Fluorouracil plus cisplatin. The study group was given paclitaxel Combined cisplatin given treatment, the clinical efficacy of the two groups were compared as well as adverse reactions. Results Compared with the control group, the clinical treatment effect was more significant in the study group and the difference was statistically significant (P <0.05). No serious complications occurred in both groups, with no significant difference (P> 0.05). Conclusion paclitaxel combined with cisplatin in the treatment of advanced esophageal cancer, can increase the survival rate of patients and promote survival time, no more serious complications.