本文介绍临床常用麻醉性镇痛药,包括吗啡、可待因、双氢可待因、芬太尼、瑞芬太尼、舒芬太尼、哌替啶、二氢埃托啡、曲马朵、丁丙诺啡和美沙酮在生物体液内的含量测定方法,如高效液相色谱法、气相色谱法、高效毛细管电泳法、气相色谱-质谱联用法及液相色谱-质谱联用法,此类方法具有灵敏度高、特异性强、准确可靠的特点,有利于临床医生更加深入地进行药物利用研究。 This article describes commonly used clinical anesthesia analgesics, including morphine, codeine, dihydrocodeine, fentanyl, remifentanil, sufentanil, meperidine, dihydroetorphine, tramadol , Buprenorphine and methadone in biological fluids, such as high performance liquid chromatography, gas chromatography, high performance capillary electrophoresis, gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry, such methods With high sensitivity, specificity, accuracy and reliability, is conducive to clinicians to conduct more in-depth study of drug use.