复方珍珠口疮颗粒中没食子酸的含量测定

来源 :中药新药与临床药理 | 被引量 : 0次 | 上传用户:feng_zj
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建立了HPLC测定复方珍珠口疮颗粒中没食子酸含量的方法,测定制剂中没食子酸含量为3.9%,明显高于生产用原料五倍子药材中没食子酸含量的2.8%,主要系生产过程中五倍子鞣质水解成没食子酸所致。 A HPLC method was established for the determination of gallic acid content in compound pearl aphtha particles. The content of gallic acid in the preparation was determined to be 3.9%, which was significantly higher than 2.8% of the gallic acid content in the raw material of production raw materials. It was mainly the hydrolysis of Chinese gallnut quail in the production process. It is caused by gallic acid.
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